The response of the brood pouch transcriptome to synthetic estrogen exposure in the Gulf pipefish (Syngnathus scovelli)
نویسندگان
چکیده
Endocrine disruptors have devastating impacts on the reproductive physiology of aquatic organisms. The Gulf pipefish, Syngnathus scovelli , is a sexually dimorphic species, which demonstrates predictable morphological, physiological, behavioral, and genetic responses to synthetic estrogen exposure. It has broad geographic range, spanning freshwater marine environments, making it potential sentinel species across wide range habitats. In this study, we investigated effects ecologically relevant levels 17α-ethinylestradiol (EE2) exposure gene expression patterns in male pipefish’s brood pouch. We also characterized extent EE2-exposed males developed coloration that are normally restricted females. identified differentially expressed genes pouches pregnant non-pregnant when were exposed 5ng/L EE2 from second eighth day pregnancy (which lasts about 2 weeks). Our result revealed several candidate role pouch’s response environmental estrogens. between mid-gestation males. found an overall greater effect transcriptomes males, may explain why estrogen-exposed exhibited difficulty receiving eggs previous studies. offspring similarly control treatments, highlighting link timing its pregnancy. These results provide insight into how breeding pipefish populations still exist even though they coastal locations where periodically potentially high concentrations endocrine-disrupting compounds. present examples female-typical development due identify pouch can be utilized as biomarkers, contributing model for ecotoxicology.
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ژورنال
عنوان ژورنال: Frontiers in Marine Science
سال: 2023
ISSN: ['2296-7745']
DOI: https://doi.org/10.3389/fmars.2023.1138597